Characterizing Postural Orthostatic Tachycardia Syndrome (POTS) in Autistic Children

Institution: University of California, Los Angeles

Project Overview

This project investigates POTS in autistic children, emphasizing the syndrome's varied presentations and comorbidities such as Ehlers-Danlos Syndrome. The study focuses on the enhanced sympathoexcitatory system in autistic individuals, contributing to sensory sensitivities and behavioral difficulties. The aim is to improve understanding and treatment approaches for autistic individuals with POTS. The study addresses the prevalence, natural history, and treatment of POTS in autistic children, considering the high incidence of comorbid conditions like Ehlers-Danlos Syndrome, Mast Cell Activation Syndrome, and others.

The study involves a detailed examination of POTS presentations in autistic children at the UCLA multidisciplinary POTS clinic. Methods include data collection, analysis, and a focus on intervention development.

The project aims to identify POTS characteristics in autistic individuals and develop tailored treatment protocols focusing on lifestyle interventions and community-based approaches.

The project deliverables include a POTS/autonomic dysfunction registry and a 6-session virtual support group curriculum. The timeline spans from July 2022 to October 2023.

Project Mentors and Contributors

Project Advisor: Rujuta B. Wilson, MD, MS
Co-Investigator: Madison Harris, OTD